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Extra- and Intracellular Calcium and Phosphate Regulation From Basic Research to Clinical Medicine by Felix Bronner

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Published by CRC .
Written in English

Subjects:

  • Clinical & Internal Medicine,
  • Pharmacology,
  • Regulation,
  • Medical / Nursing,
  • Cell Physiology,
  • Membrane Biochemistry,
  • Phosphates,
  • Science/Mathematics,
  • Nutrition,
  • Biochemistry,
  • Life Sciences - Biochemistry,
  • Health & Fitness / Nutrition,
  • Calcium,
  • Calcium-binding proteins,
  • Metabolism

Book details:

The Physical Object
FormatHardcover
Number of Pages180
ID Numbers
Open LibraryOL8258557M
ISBN 100849301882
ISBN 109780849301889

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Synopsis "Extra- and Intracellular Calcium and Phosphate Regulation: From Basic Research to Clinical Medicine" presents thinking and front-line research addressing calcium and phosphate homeostasis and related clinical problems. Major topics of this book include calcium and phosphate transport Author: Felix Bronner, Meinrad Peterlik. Extra- and Intracellular Calcium and Phosphate Regulation: From Basic Research to Clinical Medicine provides plenty of useful information for basic and clinical scientists alike, including biochemists, physiologists, cell biologists, pharmacologists, internists, orthopedic surgeons, dentists, and : $ ISBN: OCLC Number: Description: pages: illustrations ; 26 cm: Contents: Calcium entry and calcium channels / F. Bronner --Transcellular calcium transport across cultured intestinal and renal cells / R.J.M. Bindels [and others] --Phosphate transport in osteogenic cells: regulation and relation with matrix mineralization / J. Caverzasio [and others. 1. J Gen Physiol. Oct;(4) Regulation of TRPM2 by extra- and intracellular calcium. Starkus J(1), Beck A, Fleig A, Penner R. Author information: (1)Pacific Biosciences Research Center, University of Hawaii, Honolulu, HI , USA. TRPM2 is a calcium-permeable nonselective cation channel that is opened by the binding of ADP-ribose (ADPR) to a C-terminal nudix by:

Extracellular and Intracellular Regulation where it is present at more than 99% as calcium-phosphate complexes, and provides the skeleton strength and structure, making the bone a metabolic Author: Felix Bronner.   TRPM2 is a calcium-permeable nonselective cation channel that is opened by the binding of ADP-ribose (ADPR) to a C-terminal nudix domain. Channel activity is further regulated by several cytosolic factors, including cyclic ADPR (cADPR), nicotinamide adenine dinucleotide phosphate (NAADP), Ca 2+ and calmodulin (CaM), and adenosine monophosphate (AMP).Cited by: Nobuo Suzuki, in Handbook of Hormones, Regulation of Synthesis and Release. Extracellular calcium is the primary regulator of PTH secretion from the parathyroid gland. In mammals and birds, the circulating levels of PTH are greatly altered by minute changes in the blood calcium concentration [1].PTH secretion is modulated by the action of the calcium-sensing receptor (CaSR), which is. Calcium, Phosphate and Magnesium Disorders 19 [11] Gkika D, Hsu YJ, van der Kemp AW, et al. Critical role of the epithelial Ca2+ channel TRPV5 in active Ca2+ reabsorption as revealed by TRPV5.

Calcium and Phosphate levels are regulated through the coordinated action of three hormonal systems that include Vitamin D, Parathyroid Hormone (PTH), and Calcitonin. We first discuss the contributions of each hormone to calcium and phosphate regulation independently and then describe how all three hormones are coordinated in an integrated. Phosphate is the principal anion of intracellular fluid compartment. Inorganic phosphate in the plasma is mainly in two forms HPO and H 2 PO 4 -. The concentration of HPO is mmole/L and the concentration of H 2 PO 4 - mmole/L. When the total quantity of the phosphate in extracellular fluid rises so does the concentration of File Size: KB. Phosphate is present in the body in three ionic forms: H 2 PO 4−, HPO42, and PO43−. The most common form is HPO42−HPO42−. Bone and teeth bind up 85 percent of the body’s phosphate as part of calcium-phosphate salts. Phosphate is found in phospholipids, such as those that make up the cell membrane, and in ATP, nucleotides, and buffers. Intracellular Calcium Regulation Editor Felix Bronner A notable development in biological research is the recent widespread interest in the role played by calcium in cellular metabolism. Calcium homeostasis has been studied intensively for many years and mechanisms by which calcium absorption, excretion and bone deposition are effected and.